Testicular sarcoidosis is more common in African-American patients, as are other forms of sarcoidosis 1. Up to 5% of patients with chronic sarcoidosis have evidence of testicular disease on autopsy 2.
Patients may be asymptomatic or present with pain or a mass 2.
Testicular sarcoidosis should be considered in cases where there are multiple masses in the testis and epididymis 3.
On ultrasound, enlarged epididymides and multiple nodules with decreased echogenicity can be expected 2.
Expected findings on MRI include 2:
T1 C+ (Gd)
- enlarged epididymides
- may be unilateral and solitary, however, more often are multiple, small, bilateral nodular lesions
- enhancing with contrast
- T2: as above however lesions show low signal intensity
Treatment and prognosis
Excluding a testicular malignancy and preserving fertility are the main goals of treatment 1.
- 1. Rao PK, Sabanegh ES. Genitourinary sarcoidosis. (2009) Reviews in urology. 11 (2): 108-13. Pubmed
- 2. Woodward PJ, Sohaey R, O'Donoghue MJ, Green DE. From the archives of the AFIP: tumors and tumorlike lesions of the testis: radiologic-pathologic correlation. (2002) Radiographics : a review publication of the Radiological Society of North America, Inc. 22 (1): 189-216. doi:10.1148/radiographics.22.1.g02ja14189 - Pubmed
- 3. Koyama T, Ueda H, Togashi K, Umeoka S, Kataoka M, Nagai S. Radiologic manifestations of sarcoidosis in various organs. (2004) Radiographics : a review publication of the Radiological Society of North America, Inc. 24 (1): 87-104. doi:10.1148/rg.241035076 - Pubmed