Therapy-related myeloid leukemia

Last revised by Assoc Prof Craig Hacking on 18 Aug 2021

Therapy-related myeloid leukaemias, also referred to as therapy-related myeloid neoplasms, occur as a late complication after cytotoxic therapies (e.g. chemotherapy, immunosuppressive therapy, and radiation therapy) performed to treat other conditions. They represent hematological malignancies where a causal relationship has been implied, and have been recognized as distinct entities by the WHO classification of tumors of hematopoietic and lymphoid tissues

They include: 

They are known to have poor outcomes compared to the de novo cases of these entities. For further discussion, please refer to the main articles of each myeloid neoplasm. 

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