Thyroid acropachy

Dr Henry Knipe and Dr Yuranga Weerakkody et al.

Thyroid acropachy is an unusual presentation of autoimmune thyroid disease, (~1% of patients with Graves disease). It can occur in hyperthyroid, euthyroid, hypothyroid, or even post-treatment patients. It is almost always associated with thyroid ophthalmopathy

The majority of patients are smokers.

Clinically, it presents with soft tissue swelling, finger clubbing and a periosteal reaction of the extremities.

  • prominent smooth flowing periosteal reaction affecting the hands and feet. It is usually bilateral and symmetrical involving the tubular bones of hands and feet
  • may also be evidence of soft tissue swelling (especially lower limbs)
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Article information

rID: 7749
Section: Pathology
Synonyms or Alternate Spellings:

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