Toxoplasmosis is a common worldwide parasitic disease caused by the protozoan Toxoplasma gondii. It is usually an asymptomatic infection, but it is related with several sequelae when acquired in-utero or related with cerebral abscesses due to its reactivation in immunocompromised patients (e.g. HIV/AIDS).

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25-30% of the world's population is estimated to be infected by T. gondii, with a large range of prevalence between countries (from 10 to 80%) 1

Patients typically present with fever, headache, and malaise. They may later develop personality change and seizures.

Human infection can be caused either by 1:

  • directly from feline faeces
  • ingestion of tissue cysts in infected meat (consumed raw or uncooked)
  • ingestion of soil, water, or food contaminated with sporulated oocysts derived from the environment 

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The parasite was first described by Charles Nicolle and Louis Manceaux in 1909 2

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rID: 39156
Section: Gamuts
Tags: refs, cases
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