Traditional serrated adenoma

Last revised by Yuranga Weerakkody on 4 Oct 2022

Traditional serrated adenomas are a type of premalignant serrated colonic polyp.

Epidemiology

They are thought to account for <1% of all colonic polyps and 1-7% of all serrated lesions. They tend to occur in older patients (usually over 50 years) with no significant gender predilection.

Pathology

Many tend to be small (< 10 mm in size) and can be subclassified into BRAF and KRAS subtypes.

Location

They are found predominantly in the distal (left) colon with only rare occurrences in the proximal colon.

History and etymology

They were initially described by T A Longacre et al. in 1990 2.

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