Tram-track sign may refer to a variety of appearances characterized by near-parallel lines in a number of contexts and regions including:
- tram-track sign (brain): cortical calcification in Sturge-Weber syndrome
- tram-track sign (orbit): e.g. optic nerve meningioma
- tram-track sign (chest): thickened non-tapering bronchi in cylindrical bronchiectasis
- tram-track sign (bone): usually seen in HPOA on bone scan
- tram-track sign (knee): usually represents mucoid degeneration of the posterior cruciate ligament
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