Transfusion-related acute lung injury

Changed by Ian Bickle, 13 Feb 2017

Updates to Article Attributes

Body was changed:

Transfusion related acute lung injury (TRALI) is defined as non-cardiogenic pulmonary oedema temporally related to transfusion therapy. 

It tends to occur within 6 hours after a blood transfusion and requires exclusion of other alternative diagnoses such as sepsis, volume overload. 

Radiographic features

Plain radiograph

Shows features of pulmonary oedema which can progress to the alveolar and interstitial infiltrates. The lung opacities usually clear within 96 hhours in 80% of patients.

Treatment and prognosis

It tends to be self-limiting and treatment is supportive, with a prognosis substantially better than most causes of clinical acute lung injury. 

See also

  • -<p><strong>Transfusion related acute lung injury (TRALI)</strong> is defined as <a href="/articles/non-cardiogenic-pulmonary-oedema">non-cardiogenic pulmonary oedema </a>temporally related to transfusion therapy. </p><p>It tends to occur within 6 hours after a blood transfusion and requires exclusion of other alternative diagnoses such as sepsis, volume overload. </p><h4>Radiographic features</h4><h5>Plain radiograph</h5><p>Shows features of <a href="/articles/pulmonary-oedema">pulmonary oedema</a> which can progress to the alveolar and interstitial infiltrates. The lung opacities usually clear within 96 h in 80% of patients.</p><h4>Treatment and prognosis</h4><p>It tends to be self-limiting and treatment is supportive, with a prognosis substantially better than most causes of clinical acute lung injury. </p><h4>See also</h4><ul><li><a href="/articles/transfusion-associated-circulatory-overload-taco">transfusion-associated circulatory overload (TACO)</a></li></ul>
  • +<p><strong>Transfusion related acute lung injury (TRALI)</strong> is defined as <a href="/articles/non-cardiogenic-pulmonary-oedema">non-cardiogenic pulmonary oedema </a>temporally related to transfusion therapy. </p><p>It tends to occur within 6 hours after a blood transfusion and requires exclusion of other alternative diagnoses such as sepsis, volume overload. </p><h4>Radiographic features</h4><h5>Plain radiograph</h5><p>Shows features of <a href="/articles/pulmonary-oedema">pulmonary oedema</a> which can progress to the alveolar and interstitial infiltrates. The lung opacities usually clear within 96 hours in 80% of patients.</p><h4>Treatment and prognosis</h4><p>It tends to be self-limiting and treatment is supportive, with a prognosis substantially better than most causes of clinical acute lung injury. </p><h4>See also</h4><ul><li><a href="/articles/transfusion-associated-circulatory-overload-taco">transfusion-associated circulatory overload (TACO)</a></li></ul>

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