Triple screening

Last revised by Daniel J Bell on 18 Apr 2022

Triple screening refers to a screening blood test that is used to screen pregnant women for possible neural tube defects, Down syndrome and trisomy 18 in the developing fetus. It measures:

An abnormal test result doesn't indicate a birth defect, it could be because of a disparity in the estimated gestational age, similarly not all defects can be detected by this test.

Triple screens are most accurate between the 16th and the 18th weeks; however, they may be done between 15th and 22nd weeks. 

If found abnormal further ultrasound screening and amniocentesis may be suggested.

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