Trochlear nerve

Last revised by Daniel J Bell on 16 Apr 2022

The trochlear nerve is the fourth (CN IV) and thinnest cranial nerve. It exits the midbrain posteriorly, eventually passes into the cavernous sinus and into the orbit where it supplies superior oblique muscle with motor fibers (TA: nervus trochlearis or nervus cranialis IV). 

The trochlear nucleus is located in the dorsoventral midbrain, ventral to the periaqueductal grey matter. Its fibers course dorsally and decussate dorsal to the periaqueductal grey matter before exiting the brainstem immediately below the inferior colliculus. It is the only cranial nerve to exit the brainstem posteriorly.

The nerve rounds the cerebral peduncles in the ambient cistern. Eventually, along with the oculomotor nerve (CN III), it courses anteriorly between the superior cerebellar artery below and posterior cerebral artery above before piercing the dura between the free and attached edge of tentorium cerebelli.

Within the cavernous sinus, the trochlear nerve is located initially below the oculomotor nerve in the lateral wall of the sinus, although by the time it reaches the superior orbital fissure, it lies above it (outside the tendinous ring). It is the "Tarts" in this infamous mnemonic.

It enters the orbit outside the tendinous ring, between the superior ophthalmic vein and the superolateral quadrant of the ring. Once in the orbit, it arches up and medially above the superior rectus and levator palpebrae superioris to innervate the superior oblique.

Although the nerve is very thin, on high-resolution T2 weighted imaging (e.g. FIESTA/CISS) it can sometimes be visualized as a very thin structure. Dedicated higher-resolution sequences can also be performed if greater detail is required 5

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Cases and figures

  • Figure 1
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  • Figure 2: midbrain anatomy
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  • Figure 3: cavernous sinus
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  • Figure 4: orbital apex diagram
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  • Figure 5: orbit
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  • Figure 6
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  • Figure 7: cranial nerve origins (illustration)
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  • Figure 8: cranial nerves in the posterior fossa (Gray's illustration)
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