Tropical pancreatitis

Last revised by Dr Jeremy Jones on 20 Sep 2021

Tropical pancreatitis is a subtype of chronic pancreatitis associated with SPINK1 gene mutation, tropical countries, and the young age of onset. There are characteristic, large ductal calculi, which may measure up to a few centimeters in size. This is in contrast to the small, speckled calculi more commonly seen in chronic pancreatitis. Most patients are clinically present with malnutrition and steatorrhea 2. Additionally, there is a 20-fold increased risk of pancreatic cancer development.

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