Trousseau syndrome

Last revised by Rohit Sharma on 18 Jul 2022

Trousseau syndrome is an inconsistently defined entity which broadly represents the association between thromboembolism and malignancy, often prior to or concomitantly with the diagnosis of the underlying malignancy 1.

The syndrome has been variably defined to include entities such as migratory venous thrombophlebitis in malignancy, any venous or arterial thromboembolism in malignancy, any vascular sequelae of non-bacterial thrombotic endocarditis in malignancy, and hypercoagulability due to malignancy 1.

Trousseau syndrome is not to be confused with Trousseau sign.

Armand Trousseau (1801-1867), was a French physician who was the first to describe this association. Ironically he observed this exact phenomenon in himself in his upper limb prior to being diagnosed with gastric carcinoma 2.

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