Tunica vaginalis testis mesothelioma

Last revised by Dr Jeremy Jones on 20 Sep 2021

Tunica vaginalis testis mesothelioma refers to mesothelioma arising from the tunica vaginalis

Malignant mesothelioma originating from the tunica vaginalis is extremely rare. 

Patients usually present with enlarging or recurrent hydrocele, or less frequently, scrotal mass and inguinal hernia 8.

Although the exact pathophysiology is unclear, exposure to asbestos and long-standing hydrocele are considered risk factors for malignant mesothelioma of the tunica vaginalis. A history of asbestos exposure is present in <50% of patients 7.

  • it can present as single or multiple paratesticular masses, diffuse disease, or as papillary excrescences on the inner surface of a hydrocele

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