Umbilical cord thrombosis

Umbilical cord thrombosis is a potentially fatal complication and can mean either a thrombosis of the umbilical vein or either or both the umbilical arteries. Umbilical vein thrombosis occurs more frequently than thrombosis of one or both umbilical arteries (umbilical arterial thrombosis)

The estimated incidence is approximately 1 in 1300 deliveries, 1 in 1000 perinatal autopsies, and 1 in 250 high-risk gestations. There is a slight male predominance 1

Among various other aetiological factors, thrombosis of the umbilical vein can potentially occur  following cordocentesis or intra-uterine transfusion.

Associations
Ultrasound

Grey scale imaging may show focal areas or the entire cord being increased in echogenicity. Colour Doppler will confirm an absence of flow.

A poorer fetal outcome is more likely with arterial thrombosis 1. The strong association between cord thrombosis and perinatal morbidity and mortality is likely related to additional umbilical cord abnormalities, obstetrical complications, or systemic fetal conditions that are the likely cause of both the thrombosis and the poor fetal outcome. 

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Article information

rID: 14847
System: Obstetrics
Tag: cases
Synonyms or Alternate Spellings:
  • Thrombosis of the umbilical cord
  • Thrombosis of umbilical cord
  • Cord thrombosis

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