Uncinate fasciculus
Last revised by Elmira Hassanzadeh on 4 Sep 2021
Citation, DOI, disclosures and article data
Citation:
Sciacca F, Hassanzadeh E, Murphy A, et al. Uncinate fasciculus. Reference article, Radiopaedia.org (Accessed on 06 Oct 2024) https://doi.org/10.53347/rID-70675
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rID:
70675
Article created:
30 Aug 2019,
Francesco Sciacca ◉
Disclosures:
At the time the article was created Francesco Sciacca had no recorded disclosures.
View Francesco Sciacca's current disclosures
Last revised:
4 Sep 2021,
Elmira Hassanzadeh
Disclosures:
At the time the article was last revised Elmira Hassanzadeh had no recorded disclosures.
View Elmira Hassanzadeh's current disclosures
Revisions:
4 times, by
4 contributors -
see full revision history and disclosures
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The uncinate fasciculus is a white matter tract that connects the uncus (Brodmann area 35), the anterior temporal areas (temporal pole; Brodmann area 38), the amygdala and the hippocampal gyrus (Brodmann areas 36 and 30) with areas of the frontal lobe (polar and orbital cortex); runs - forming a curve (hook-shaped morphology) around the common trunk of the lateral sulcus (Sylvian fissure) - ventrally to the inferior front-occipital fasciculus.
Related pathology
The uncinate fasciculus is thought to be part of the circuitry involved in the retrieval of word form for proper names 6. In fact, the resection of the uncinate fasciculus, in its frontal or temporal part, has long-lasting consequences for face naming.
References
- 1. Kenichi Oishi, Andreia V. Faria, Peter C. M. van Zijl, Susumu Mori. MRI Atlas of Human White Matter. (2010) ISBN: 9780123820815
- 2. Wakana S, Jiang H, Nagae-Poetscher LM, van Zijl PC, Mori S. Fiber tract-based atlas of human white matter anatomy. (2004) Radiology. 230 (1): 77-87. doi:10.1148/radiol.2301021640 - Pubmed
- 3. Dini LI, Vedolin LM, Bertholdo D, Grando RD, Mazzola A, Dini SA, Isolan GR, da Costa JC, Campero A. Reproducibility of quantitative fiber tracking measurements in diffusion tensor imaging of frontal lobe tracts: A protocol based on the fiber dissection technique. (2013) Surgical neurology international. 4: 51. doi:10.4103/2152-7806.110508 - Pubmed
- 4. Alvin M. Burt. Trattato di neuroanatomia. (1996) ISBN: 9788829913169
- 5. Dario Grossi, Luigi Trojano. Neuropsicologia dei lobi frontali. Sindromi disesecutive e disturbi del comportamento. (2019) ISBN: 9788815246066
- 6. Papagno C, Miracapillo C, Casarotti A, Romero Lauro LJ, Castellano A, Falini A, Casaceli G, Fava E, Bello L. What is the role of the uncinate fasciculus? Surgical removal and proper name retrieval. (2011) Brain : a journal of neurology. 134 (Pt 2): 405-14. doi:10.1093/brain/awq283 - Pubmed
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