Unclassified hepatic adenoma
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Unclassified hepatic adenomas refer to the 5-10% of hepatocellular adenomas subtype that lack known genetic abnormalities 1,2. These adenomas cannot be further categorized genetically or histologically as inflammatory adenomas, HNF 1 alpha mutated adenomas or beta catenin mutated adenomas.
The clinical features of these adenomas remain poorly understood. No specific MR imaging features have been proposed to identify unclassified hepatocellular adenomas 1.
- 1. Venkata S. Katabathina, Christine O. Menias, Alampady K. P. Shanbhogue, Jaishree Jagirdar, Raj Mohan Paspulati, Srinivasa R. Prasad. Genetics and Imaging of Hepatocellular Adenomas: 2011 Update. (2011) RadioGraphics. doi:10.1148/rg.316115527
- 2. Kouki Hoshino, Norifumi Harimoto, Ryo Muranushi, Kei Hagiwara, Takahiro Yamanaka, Norihiro Ishii, Mariko Tsukagoshi, Takamichi Igarashi, Akira Watanabe, Norio Kubo, Kenichiro Araki, Ran Tomomasa, Sumihito Nobusawa, Shinichi Aishima, Osamu Nakashima, Ken Shirabe. Unclassified hepatocellular adenoma with histological brown pigment deposition and serum PIVKA-II level elevation: a case report. (2020) Surgical Case Reports. 6 (1): 1. doi:10.1186/s40792-020-00853-6