Undifferentiated carcinoma of the endometrium

Last revised by David Luong on 18 Jun 2021

Undifferentiated carcinoma of the endometrium a is rare histological subtype of endometrial cancer. It is considered a high grade carcinoma, carries a poor prognosis and is often under-recognized 1.

Epidemiology

It is thought to represent approximately 1-9% of endometrial cancers 1,6.

Pathology

They have no evidence of glandular or epithelial differentiation. They can be further subdivided into large cell, intermediate or small cell types. Some carcinomas carry neuroendocrine expression 4

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