Unicentric Castleman disease

Last revised by Rohit Sharma on 2 Jul 2023

Unicentric Castleman disease (UCD) is considered the more common form of Castleman disease and involves one or more enlarged lymph nodes in a single region of the body that demonstrates histopathologic features that have features of Castleman disease. A subset of patients can have systemic symptoms.


Unicentric Castleman disease is most commonly found in the mediastinum, where it appears as an avidly enhancing mass that displaces surrounding structures 1.

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Cases and figures

  • Case 1: right axilla
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  • Case 2
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  • Case 3
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