Unicentric Castleman disease
Last revised by Rohit Sharma on 2 Jul 2023
Citation, DOI, disclosures and article data
Citation:
Weerakkody Y, Ashraf A, Sharma R, et al. Unicentric Castleman disease. Reference article, Radiopaedia.org (Accessed on 08 Oct 2024) https://doi.org/10.53347/rID-95611
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rID:
95611
Article created:
9 Dec 2021,
Yuranga Weerakkody ◉
Disclosures:
At the time the article was created Yuranga Weerakkody had no recorded disclosures.
View Yuranga Weerakkody's current disclosures
Last revised:
2 Jul 2023,
Rohit Sharma ◉
Disclosures:
At the time the article was last revised Rohit Sharma had no financial relationships to ineligible companies to disclose.
View Rohit Sharma's current disclosures
Revisions:
5 times, by
5 contributors -
see full revision history and disclosures
Systems:
Tags:
Synonyms:
- Unicentric Castleman disease (UCD)
Unicentric Castleman disease (UCD) is considered the more common form of Castleman disease and involves one or more enlarged lymph nodes in a single region of the body that demonstrates histopathologic features that have features of Castleman disease. A subset of patients can have systemic symptoms.
Location
Unicentric Castleman disease is most commonly found in the mediastinum, where it appears as an avidly enhancing mass that displaces surrounding structures 1.
References
- 1. Bonekamp D, Horton K, Hruban R, Fishman E. Castleman Disease: The Great Mimic. Radiographics. 2011;31(6):1793-807. doi:10.1148/rg.316115502 - Pubmed
- 2. Hill A, Tirumani S, Rosenthal M et al. Multimodality Imaging and Clinical Features in Castleman Disease: Single Institute Experience in 30 Patients. Br J Radiol. 2015;88(1049):20140670. doi:10.1259/bjr.20140670 - Pubmed
- 3. Kligerman S, Auerbach A, Franks T, Galvin J. Castleman Disease of the Thorax: Clinical, Radiologic, and Pathologic Correlation:From the Radiologic Pathology Archives. Radiographics. 2016;36(5):1309-32. doi:10.1148/rg.2016160076 - Pubmed
- 4. Zhao S, Wan Y, Huang Z, Song B, Yu J. Imaging and Clinical Features of Castleman Disease. Cancer Imaging. 2019;19(1):53. doi:10.1186/s40644-019-0238-0 - Pubmed
- 5. Ye B, Gao S, Li W et al. A Retrospective Study of Unicentric and Multicentric Castleman’s Disease: A Report of 52 Patients. Med Oncol. 2009;27(4):1171-8. doi:10.1007/s12032-009-9355-0