Upper lobe fibrocavitary pattern of mycobacterium avium complex pulmonary disease

Last revised by Yuranga Weerakkody on 12 May 2022

Upper lobe fibrocavitary pattern of mycobacterium avium complex pulmonary disease is morphological from pulmonary mycobacterium avium complex infection although it is worthwhile understanding that there can be a spectrum of the disease with mixed forms. 

This form had been initially the traditionally recognized presentation of lung disease from mycobacterium avium complex infection.

It is reported to usually occur in men with a history of cigarette smoking, excessive alcohol use, and underlying lung disease. Presentation is usually in the late 40s and early 50s (although there can be considerable variation). 

Typically presents as apical fibro-cavitary lung disease with large cavities primarily located in the upper lobe.

If untreated, this form has been described to be progressive within relatively short time periods (e.g. 1 to 2 years) eventually causing extensive cavitary lung destruction and potentially leading to respiratory failure 1.

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Cases and figures

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