Usual interstitial pneumonia (American thoracic society criteria for histopathological diagnosis)

Last revised by Jeremy Jones on 18 Feb 2018

Citation, DOI, disclosures and article data

Citation:

Rezaee A, Jones J, Goel A, et al. Usual interstitial pneumonia (American thoracic society criteria for histopathological diagnosis). Reference article, Radiopaedia.org (Accessed on 19 Apr 2024) https://doi.org/10.53347/rID-45288

DOI:

https://doi.org/10.53347/rID-45288

Permalink:

https://radiopaedia.org/articles/45288

rID:

45288

Article created:

19 May 2016, Amir Rezaee

Disclosures:

At the time the article was created Amir Rezaee had no recorded disclosures.

View Amir Rezaee's current disclosures

Last revised:

18 Feb 2018, Jeremy Jones ◉

Disclosures:

At the time the article was last revised Jeremy Jones had no recorded disclosures.

View Jeremy Jones's current disclosures

Revisions:

5 times, by 5 contributors - see full revision history and disclosures

Systems:

Chest

Synonyms:

ATS criteria for diagnosis of UIP on pathology
American Thoracic Society (ATS) critera for histopathological diagnosis of usual interstitial pneumonia (UIP)
American Thoracic Society criteria for histopathological diagnosis of usual interstitial pneumonia

American Thoracic Society (ATS) criteria for the histopathological diagnosis of usual interstitial pneumonia (UIP) are as follows:

advanced subpleural or paraseptal fibrosis +/- honeycombing
patchy temporally heterogeneous fibrosis
fibroblastic foci
the absence of features against UIP
- inflammatory cells
- granulomas
- organizing pneumonia

The most important difference is that presence of honeycombing is not a major criterion for the diagnosis of UIP in pathology as opposed to chest HRCT, although in the majority of cases microscopic fibrotic cysts can be seen which could be considered precursors of the macroscopic subpleural honeycombing on HRCT chest.