Uterine sarcoma is a malignant uterine tumor thats is composed of part or all sarcomatous (mesodermal) elements. They however account for a minority of all uterine malignancies (1-6% 3,4).
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Pathology
Classification
They can be broadly classified as pure or mixed 4:
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mixed
- carcinosarcoma of the uterus: (previously known as malignant mixed Müllerian tumor of the uterus) ~50-70%, most common sarcoma
- mixed uterine leiomyosarcoma and endometrial stromal sarcoma
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pure
- uterine leiomyosarcoma: ~33-50%
- endometrial stromal sarcoma: 10%
- fibrosarcoma of the uterus: rare
- rhabdomyosarcoma of the uterus: rare
- liposarcoma of the uterus: rare
- angiosarcoma of the uterus: rare
Prognosis
In general they are aggressive lesions characterized by early dissemination.