Van der Woude syndrome

Dr Daniel J Bell and Radswiki et al.

van der Woude syndrome (VWS) is characterized by the association of congenital lower lip fistulae/pits with cleft lip and/or palate.

It is one of the most common clefting syndromes in humans 1 and affected individuals have a high prevalence of hypodontia.



It carries an autosomal dominant inheritance. Although caused by a single gene mutation, Van der Woude syndrome has variable phenotypic expression.

Article information

rID: 15163
Section: Syndromes
Synonyms or Alternate Spellings:
  • Van der Woude syndrome (VWS)

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