Vasogenic cerebral oedema refers to a type of cerebral oedema in which the blood brain barrier (BBB) is disrupted (cf. cytotoxic cerebral oedema, where the BBB is intact). It is an extracellular oedema which mainly affects the white matter via leakage of fluid from capillaries.
It is most frequently seen around brain tumours (both primary and secondary) and cerebral abscesses, though some vasogenic oedema may be seen around maturing cerebral contusion and cerebral haemorrhage.
- grey-white matter differentiation is maintained and the oedema involves mainly white matter, extending in finger-like fashion
- secondary effects of vasogenic oedema are similar to cytotoxic oedema, with effacement of cerebral sulci, with or without midline shift
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