Vasogenic cerebral oedema

Vasogenic cerebral oedema refers to a type of cerebral oedema in which the blood brain barrier (BBB) is disrupted (cf. cytotoxic cerebral oedema, where BBB is intact). It is an extracellular oedema which mainly affects the white matter via leakage of fluid from capillaries.

It is most frequently seen around brain tumours (both primary and secondary) and cerebral abscesses, although some vasogenic oedema may be seen around maturing cerebral contusion and cerebral haemorrhage.

Radiographic features

CT
  • grey-white matter differentiation is maintained and the oedema involves mainly white matter, extending in finger-like fashion
  • secondary effects of vasogenic oedema are similar to cytotoxic oedema, with effacement of cerebral sulci, with or without midline shift
MRI
  • hyperintense T2 and FLAIR signals, which do not show restricted diffusion 2 (cf. cytotoxic cerebral oedema, which shows diffusion restriction)
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Article Information

rID: 24486
Tags: refs, cases
Synonyms or Alternate Spellings:
  • Vasogenic cerebral edema
  • Vasogenic edema
  • Vasogenic brain oedema
  • Vasogenic brain edema

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Cases and Figures

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    Case 1 - breast cancer metastases
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     Case 2 - lung cancer metastases
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