Virtual non-contrast imaging

Andrew Murphy et al.

Virtual non-contrast imaging is an image post-processing technique used to create 'non-contrast' images of contrast-enhanced scans via the subtraction of iodine. It is an imaging technique unique to dual energy CT.

Clinical applications

Virtual non-contrast imaging has the potential to replace the traditional non-contrast CT scan in multiphasic imaging 1, yet the application suitability varies from study to study. Attenuation values are found to yield 'similar readings' to traditional non-contrast studies 2,3; the clinical relevance of these discrepancies is an ongoing area of research.

Differentiation of hemorrhage from iodinated contrast

Contrast staining of the brain parenchyma post iodinated contrast can lead to interpretation issues, especially when the density of contrast is similar to that of blood. Virtual non-contrast imaging is an accurate 4 method in differentiating intracranial hemorrhage from iodinated contrast staining following interventional procedures such as endovascular clot retrieval.

Physics and imaging technology: CT
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Article information

rID: 66311
Section: Radiography
Tag: cases
Synonyms or Alternate Spellings:
  • Virtual non-contrast
  • Virtual unenhanced
  • VNC

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Cases and figures

  • Case 1: virtual non-contrast head post endovascular clot retrieval
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