Vitamin B6

Last revised by Dr Daniel J Bell on 02 Aug 2021

Vitamin B6 is a group of water-soluble vitamins, part of the vitamin B complex, and that are derivatives of pyridine, the main vitamers are known as pyridoxine, pyridoxal and pyridoxamine. All three form part of the coenzyme pyridoxal 5'-phosphate (PLP) which is involved in many cellular reactions including the synthesis of several amino acids and the metabolism of glucose and lipids. Vitamin B6 is one of the hematinics.

The antitubercular drug isoniazid is an inactive derivative of pyridoxal phosphate, hence vitamin B6 needs to be co-administered to patients on isoniazid.

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