Vulval neoplasms

Vulval neoplasms are rare and mostly seen in elderly female patients. Squamous cell carcinoma (SCC) is the most common malignancy of the vulva and only 30% of them are associated with oncogenic human papillomaviruses (HPVs).

Pathology

Squamous neoplastic lesions 
Premalignant 
  • classic vulvar intraepithelial neoplasm (classic VIN): precursors of the basaloid SCCs
  • differentiated vulvar intraepithelial neoplasm (differentiated VIN): precursors of the keratinizing SCCs
Malignant squamous cell carcinoma
  • invasive basaloid and warty squamous cell carcinomas: 30% of cases, associated with human papillomavirus (HPV)
  • keratinizing squamous cell carcinoma: 70%, not associated with HPV
Glandular neoplastic lesions 
Malignant melanoma 

Article information

rID: 38914
Section: Gamuts
Tag: refs, cases
Synonyms or Alternate Spellings:
  • vulval malignancies
  • vulval neoplasm
  • vulval neoplasms

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