Vulval neoplasms

Vulval neoplasms are rare and mostly seen in an elderly female patients. Squamous cell carcinoma is most common malignancy of the vulva which only 30% of them are associated with oncogenic HPV viruses.

Pathology

Squamous neoplastic lesions 
Premalignant 
  • classic vulvar intraepithelial neoplasm (classic VIN): precursors of the basaloid SCCs
  • differentiated vulvar intraepithelial neoplasm (differentiated VIN): precursors of the keratinizing SCCs
Malignant squamous cell carcinoma
  • invasive basaloid and warty squamous cell carcinomas: 30% of cases, associated with HPV
  • keratinizing squamous cell carcinoma: 70%, not associated with HPV
Glandular neoplastic lesions 
  • similar to their breast lesion counterparts
    • papillary hidradenoma 
    • extramammary Paget disease
Malignant melanoma 
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Article Information

rID: 38914
System: Gynaecology
Section: Gamuts
Tags: refs, cases
Synonyms or Alternate Spellings:
  • vulval malignancies
  • vulval neoplasm
  • vulval neoplasms

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