WAGR syndrome
Last revised by Naim Qaqish on 26 Sep 2020
Citation, DOI, disclosures and article data
Citation:
Weerakkody Y, Qaqish N, Skalina T, et al. WAGR syndrome. Reference article, Radiopaedia.org (Accessed on 23 Apr 2024) https://doi.org/10.53347/rID-7903
rID:
7903
Article created:
22 Dec 2009,
Yuranga Weerakkody ◉
Disclosures:
At the time the article was created Yuranga Weerakkody had no recorded disclosures.
View Yuranga Weerakkody's current disclosures
Last revised:
26 Sep 2020,
Naim Qaqish
Disclosures:
At the time the article was last revised Naim Qaqish had no recorded disclosures.
View Naim Qaqish's current disclosures
Revisions:
7 times, by
6 contributors -
see full revision history and disclosures
Systems:
Sections:
The WAGR syndrome or complex stands for:
- Wilms tumors (greatly increased risk)
- aniridia
- genitourinary anomalies
- intellectual retardation (disability)
Pathology
Genetics
Occurs from a mutation related to chromosome 11p13 3 which is in close proximity to the WT1 gene.
References
- 1. Aquisto TM, Yost R, Marshall KW. Best cases from the AFIP: anaplastic wilms tumor: radiologic and pathologic findings. Radiographics. 2004;24 (6): 1709-13. Radiographics (full text) - doi:10.1148/rg.246045040 - Pubmed citation
- 2. Lowe LH, Isuani BH, Heller RM et-al. Pediatric renal masses: Wilms tumor and beyond. Radiographics. 2000;20 (6): 1585-603. Radiographics (full text) - Pubmed citation
- 3. Fischbach BV, Trout KL, Lewis J et-al. WAGR syndrome: a clinical review of 54 cases. Pediatrics. 2005;116 (4): 984-8. doi:10.1542/peds.2004-0467 - Pubmed citation