Weber-Christian disease or Pfeifer-Weber-Christian disease or idiopathic relapsing febrile nodular non-suppurative panniculitis was initially defined as a rare inflammatory disorder of unknown aetiology affecting subcutaneous adipose tissue inter alia 1.
However, the understanding of lobular panniculitis has expanded and cases that were once diagnosed in the "water basket" of “Weber-Christian” disease are with modern histology and immunopathology recognised to be clearly definable and separate entities comprising:
- lupus panniculitis
- cytophagic histiocytic panniculitis
- α 1-antitrypsin deficiency
- factitial panniculitis
- traumatic panniculitis
Most authors suggest the term abandoned or even buried 2-4.
- 1. Khan GA, Lewis FI. Recognizing Weber-Christian disease. Tenn Med. 1997;89 (12): 447-9. Pubmed citation
- 2. Rapini RP. Practical Dermatopathology, 2e. Saunders. ISBN:0323066585. Read it at Google Books - Find it at Amazon Ch. 16
- 3. Firestein GS, Budd RC, MSc SEGMD et-al. Kelley's Textbook of Rheumatology. Saunders. ISBN:1437717381. Read it at Google Books - Find it at Amazon Ch. 43, pp. 599-616
- 4. DipRCPath JECMD, FRCPath TBMDP, Lazar AJ et-al. McKee's Pathology of the Skin. Saunders. ISBN:1416056491. Read it at Google Books - Find it at Amazon