Weber syndrome

Last revised by Mostafa Elfeky on 23 Dec 2021

Weber syndrome is a midbrain stroke syndrome that involves the cerebral peduncle and the ipsilateral fascicles of the oculomotor nerve 1-3,5. Occasionally the substantia nigra can also be involved 5

It is usually caused by an ischemic stroke, typically involving branches of the posterior cerebral artery 1-3.

Imaging may be helpful to connect the neurological symptoms with a single causative lesion.

The imaging appearance of Weber and Benedikt syndromes may be similar, as both result from an insult to the oculomotor nuclear complex 1-3, however the latter syndrome also involves the red nucleus in the midbrain tegmentum.

The syndrome was first described by Sir Hermann Weber (1823-1918), a German-born English physician, in 1863 4.

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Cases and figures

  • Case 1: DWI
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  • Case 1: FLAIR
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  • Case 2
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  • Case 3: DWI
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