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- ipsilateral CN III palsy
- afferent pupillary defect
- contralateral hemiplegia or hemiparesis
- contralateral parkinsonian rigidity (only if substantia nigra involved) 5
Imaging may be helpful to connect the neurological symptoms with a single causative lesion.
The imaging appearance of Weber and Benedikt syndromes may be similar, as both result from an insult to the oculomotor nuclear complex 1-3, however the latter syndrome also involves the red nucleus in the midbrain tegmentum.
History and etymology
The syndrome was first described by Sir Hermann Weber (1823-1918), a German-born English physician, in 1863 4.