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Wheel within a wheel sign (hepatic candidiasis)

Last revised by Daniel J Bell on 27 Apr 2018

Citation, DOI, disclosures and article data

Citation:

Mehdi E, Bell D, Knipe H, et al. Wheel within a wheel sign (hepatic candidiasis). Reference article, Radiopaedia.org (Accessed on 06 Oct 2024) https://doi.org/10.53347/rID-16489

DOI:

https://doi.org/10.53347/rID-16489

Permalink:

https://radiopaedia.org/articles/16489

rID:

16489

Article created:

22 Jan 2012, Elnur Mehdi

Disclosures:

At the time the article was created Elnur Mehdi had no recorded disclosures.

View Elnur Mehdi's current disclosures

Last revised:

27 Apr 2018, Daniel J Bell ◉

Disclosures:

At the time the article was last revised Daniel J Bell had no recorded disclosures.

View Daniel J Bell's current disclosures

Revisions:

6 times, by 5 contributors - see full revision history and disclosures

Systems:

Hepatobiliary

Sections:

Signs

Synonyms:

Wheel within a wheel sign in hepatic candidiasis

The wheel within a wheel sign describes one of several possible ultrasound findings of hepatic candidiasis. The finding consists of a round lesion with three layers corresponding to the following histopathological changes ²:

peripheral hypoechoic area (fibrosis)
middle hyperechoic area (inflammatory cells)
central hypoechoic area (necrosis)

The histopathologic correlates were shown via an animal model.

This appearance is in contrast to the more common bull’s-eye sign ultrasound finding, which consists of a central echogenic nidus surrounded by a hypoechoic rim.

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