Citation, DOI, disclosures and article data
Citation:
Gaillard F, Sharma R, Bell D, et al. Whipple triad. Reference article, Radiopaedia.org (Accessed on 27 Mar 2025) https://doi.org/10.53347/rID-12909
Whipple triad is the clinical presentation of pancreatic insulinoma and consists of:
- fasting hypoglycaemia (<50 mg/dL or <2.7 mmol/L)
- symptoms of hypoglycaemia
- immediate relief of symptoms after the administration of intravenous glucose
History and etymology
The triad and also the Whipple procedure were both named after the American surgeon, Allen Oldfather Whipple (1881-1963) 2.
However Whipple disease was named for a different Whipple.
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1. Gouya H, Vignaux O, Augui J et-al. CT, endoscopic sonography, and a combined protocol for preoperative evaluation of pancreatic insulinomas. AJR Am J Roentgenol. 2003;181 (4): 987-92. AJR Am J Roentgenol (full text) - Pubmed citation
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2. IN MEMORIAM ALLEN O. WHIPPLE, MD. 1881-1963. (1963) Annals of surgery. 158: 148. Pubmed
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