Whipple triad

Last revised by Rohit Sharma on 02 Jul 2022

Whipple triad is the clinical presentation of pancreatic insulinoma and consists of:

  • fasting hypoglycemia (<50 mg/dL or <2.7 mmol/L)
  • symptoms of hypoglycemia
  • immediate relief of symptoms after the administration of intravenous glucose

    History and etymology

    The triad and also the Whipple procedure were both named after the American surgeon, Allen Oldfather Whipple (1881-1963) 2​.

    However Whipple disease was named for a different Whipple.

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