White grey sign

Last revised by Bruno Di Muzio on 25 Apr 2019

Citation, DOI, disclosures and article data

Citation:

Zeineh M, Di Muzio B, White grey sign. Reference article, Radiopaedia.org (Accessed on 25 Apr 2024) https://doi.org/10.53347/rID-67680

DOI:

https://doi.org/10.53347/rID-67680

Permalink:

https://radiopaedia.org/articles/67680

rID:

67680

Article created:

19 Apr 2019, Michael Zeineh

Disclosures:

At the time the article was created Michael Zeineh had no recorded disclosures.

View Michael Zeineh's current disclosures

Last revised:

25 Apr 2019, Bruno Di Muzio ◉ ◈

Disclosures:

At the time the article was last revised Bruno Di Muzio had no recorded disclosures.

View Bruno Di Muzio's current disclosures

Revisions:

4 times, by 2 contributors - see full revision history and disclosures

Systems:

Central Nervous System

Sections:

Anatomy

White grey sign is useful for identifying the central sulcus on MRI images. It reflects that fact that primary motor and sensory cortex has more myelin in it than other cortices. This results in a whitening of the cortex on T1-weighted imaging, especially noticeable at higher field strengths. One can quickly assess the grey-white junction, and confirm that the central sulcus exhibits reduced contrast on both sides. This sign is synergistic with a differential in cortical thickness across the pre and postcentral gyri in the central sulcus (pre=thicker and post=thinner). This sign is also present in other primary cortices: primary visual and primary auditory.