The WHO classification of odontogenic and maxillofacial bone tumors, last published in 2017, is a subset of the WHO classification of head and neck tumors (4th edition), which lays out a histological classification system for neoplasms and other tumors related to the odontogenic apparatus.
Classification
Malignant odontogenic tumors
-
odontogenic carcinomas
- ameloblastic carcinoma
- primary intraosseous carcinoma, not otherwise specified
- sclerosing odontogenic carcinoma
- clear cell odontogenic carcinoma
- ghost cell odontogenic carcinoma
- odontogenic carcinosarcoma
- odontogenic sarcomas
Benign odontogenic tumors
-
benign epithelial odontogenic tumors
-
ameloblastoma
- ameloblastoma, unicystic type
- ameloblastoma, extraosseous/peripheral type
- metastasizing ameloblastoma
- squamous odontogenic tumor
- calcifying epithelial odontogenic tumor
- adenomatoid odontogenic tumor
-
ameloblastoma
-
benign mixed epithelial and mesenchymal odontogenic tumors
- ameloblastic fibroma
- primordial odontogenic tumor
- odontoma
- dentinogenic ghost cell tumor
- benign mesenchymal odontogenic tumors
Odontogenic cysts
-
odontogenic cysts of inflammatory origin
- radicular cyst
- inflammatory collateral cysts
- odontogenic and non-odontogenic developmental cysts
Malignant maxillofacial bone and cartilage tumors
Benign maxillofacial bone and cartilage tumors
- chondroma
- osteoma
- melanotic neuroectodermal tumor of infancy
- chondroblastoma
- chondromyxoid fibroma
- osteoid osteoma
- osteoblastoma
- desmoplastic fibroma
Fibro-osseous and osteochondromatous lesions
- ossifying fibroma
- familial gigantiform cementoma
- fibrous dysplasia
- cemento-osseous dysplasia
- osteochondroma
Giant cell lesions and simple bone cyst
- central giant cell granuloma
- peripheral giant cell granuloma
- cherubism
- aneurysmal bone cyst
- simple bone cyst
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