WHO classification of tumors of bone

Last revised by Joshua Yap on 15 Oct 2022

The World Health Organization (WHO) classification of bone tumors is the most widely used pathologic classification system for such disorders. The current revision, part of the 5th edition of the WHO series, was published in 2020 and is reflected in the article below 1.

Newly introduced entities include the following 1:

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Cases and figures

  • Figure 1: bone lesions below age 30
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  • Case 1: osteochondroma
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  • Figure 2: bone lesions above age 30
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  • Case 2: enchondroma
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  • Case 3: chondromyxoid fibroma
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  • Case 4: subungual exostosis
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  • Case 5: bizarre parosteal osteochondromatous proliferation (Nora lesion)
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  • Case 6: synovial chondromatosis
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  • Case 7: chondroblastoma
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  • Case 8: chondrosarcoma
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  • Case 9: osteoma
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  • Case 10: osteoid osteoma
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  • Case 11: osteoblastoma
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  • Case 12: osteosarcoma
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  • Case 13: desmoplastic fibroma
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  • Case 14: hemangioma
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  • Case 15: aneurysmal bone cyst
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  • Case 16: aneurysmal bone cyst (MRI)
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  • Case 17: giant cell tumor
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  • Case 18: non-ossifying fibroma
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  • Case 19: chordoma
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  • Case 20: osteofibrous dysplasia
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  • Case 21: adamantinoma
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  • Case 22: simple bone cyst
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  • Case 23: fibrous dysplasia
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  • Case 24: lipoma of bone
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  • Case 25: undifferentiated pleomorphic sarcoma
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  • Case 26: bone metastasis
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  • Case 27: solitary plasmacytoma of bone
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  • Case 28: primary non-Hodgkin lymphoma of bone
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  • Case 29: Langerhans cell histiocytosis
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  • Case 30: Erdheim-Chester disease
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