WHO histological classification of benign renal neoplasms

Last revised by Dr Daniel J Bell on 04 Oct 2021

Benign renal tumors were histologically classified according to the World Health Organizatiοn​ 1. This is the subset of entities in the 2016 WHO classification of renal tumors that are associated with an International Classification of Diseases for Oncology (ICD-O) behavior code of 0, indicating benign tumors. This article also separately includes entities with a behavior code of 1, indicating unspecified, borderline, or uncertain behavior. The remainder of entities in the WHO classification are considered malignant.

Benign tumors

Renal cell tumors
Metanephric tumors
Nephroblastic and cystic tumors occurring mainly in children
Mesenchymal tumors occurring mainly in children
Mesenchymal tumors occurring mainly in adults
Mixed epithelial and stromal tumor family
Neuroendocrine tumors

Tumors of unspecified, borderline, or uncertain behavior

Renal cell tumors
Metanephric tumors
Nephroblastic and cystic tumors occurring mainly in children
Mesenchymal tumors occurring mainly in children
Mesenchymal tumors occurring mainly in adults

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Cases and figures

  • Case 1: renal angiomyolipoma
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