Widening of the diploic space

Widening of the diploic space refers to expansion of the cancellous (spongy) bone between the inner and outer tables of the calvaria. The diploic space is the medullary cavity of the skull, and a location of normal physiologic hematopoiesis in adults. Thus, expansion of this structure most commonly occurs in the setting of chronically increased intramedullary hematopoiesis. The widened appearance is most commonly bilateral.


Most commonly caused by systemic pathologies such as:

Article information

rID: 53107
Synonyms or Alternate Spellings:
  • Diploic widening
  • Widening of diploic space
  • Diploic space widening

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Cases and figures

  • Case 1: thalassemia major
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