Wormian bone

Wormian bones (also knows as intrasutural bones) is the name given to the additional small bones sometimes found between the cranial sutures of the bones of the skull vault, most commonly in relation to the lambdoid suture. Some reserve the term Wormian bones to just the intrasutural bones proximate to the lambdoid suture.

Some consider them abnormal only if greater than 10 in number.

Epidemiology

The reported incidence is variable, ranging from around 10% (in Caucasian skulls) and 40% (in Indian skulls) to 80% (in Chinese skulls) ^ref. In general, males are more frequently affected than females ^ref.

Associations

Their associations are various, and include:

• pyknodysostosis
• osteogenesis imperfecta
• rickets
• Menkes disease (kinky hair kinky vessel syndrome)
• cleidocranial dysostosis
• hypothyroidism
• hypophosphatasia
• otopalatodigital syndrome
• primary acro-osteolysis (Hajdu-Cheney syndrome)
• pachydermoperiostosis
• progeria
• Down syndrome

Wormian bones can also be idiopathic (anatomical variant). 

A useful mnemonic is PORKCHOPS.

Locations

• lambdoid suture: most common
• lambda (also known as the pre-interparietal or inca bone)
• pterion: up to 12%; former anterolateral fontanelle (also known as the epipteric bone or pterion ossicle)
• sagittal and coronal sutural bones: uncommon

History and etymology

Wormian bones are named after the Danish physician, theologian and antiquary Ole Worm (Olaus Wormius) (1588-1654) ⁴, who first described them.