Wunderlich syndrome

Mr Andrew Murphy â—‰ and Dr Praveen Jha et al.

Wunderlich syndrome is a rare condition, in which spontaneous nontraumatic renal haemorrhage occurs into the subcapsular and perirenal spaces 2.

Wunderlich syndrome is clinically characterized by Lenk's triad

  • acute flank pain
  • flank mass
  • hypovolaemic shock

Haemorrhage in the perinephric space, often with a primary lesion seen within the kidney, e.g. angiomyolipoma, renal cell carcinoma.

If the haemorrhage is self-limiting and the patient is responsive to fluid resuscitation, the patient can be managed conservatively. Angiographic selective embolisation may be pursued in haemodynamically stable patients. In haemodynamically unstable patients, emergent nephrectomy (partial or total) is often required 3.

It is named after the German physician Carl Reinhold August Wunderlich.

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Article information

rID: 16265
System: Urogenital
Section: Syndromes
Synonyms or Alternate Spellings:
  • Wunderlich's syndrome

Cases and figures

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