Wunderlich syndrome

Wunderlich syndrome is a rare condition, in which spontaneous nontraumatic renal hemorrhage occurs into the subcapsular and perirenal spaces 2.

Wunderlich syndrome is clinically characterized by Lenk's triad:

  • acute flank pain
  • flank mass
  • hypovolemic shock

Hemorrhage in the perinephric space, often with a primary lesion seen within the kidney, e.g. angiomyolipoma, renal cell carcinoma.

If the hemorrhage is self-limiting and the patient is responsive to fluid resuscitation, the patient can be managed conservatively. Angiographic selective embolization may be pursued in haemodynamically stable patients. In haemodynamically unstable patients, emergent nephrectomy (partial or total) is often required 3.

It is named after the German physician Carl Reinhold August Wunderlich.

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Article information

rID: 16265
System: Urogenital
Section: Syndromes
Synonyms or Alternate Spellings:
  • Wunderlich's syndrome

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Cases and figures

  • Retroperitoneal h...
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  • Case 4
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