Wyburn-Mason syndrome

Wyburn-Mason syndrome (also known as Bonnet-Dechaume-Blanc syndrome) is a rare, nonhereditary neurocutaneous disorder that typically presents with unilateral vascular malformations that primarily involve the brain, orbits and facial structures. It is currently classified as a craniofacial arteriovenous metameric syndrome (CAMS) 3-4


Features include:

  • facial vascular nevus
  • visual pathway and orbital arteriovenous malformations (AVMs), e.g. racemose angioma
  • intracranial arteriovenous malformations (AVMs)

Cases of bilateral malformations have been described and there is an association with subarachnoid hemorrhage.

History and etymology

  • Roger Wyburn-Mason (1911-1983), British neurologist at the National Hospital of Neurology and Neurosurgery (Queen Square), London
  • Paul Bonnet (1894-1959), French ophthalmologist
  • Jean Dechaume (1896-1968), French neurosurgeon
  • Eugene Blanc (1888-1961), French neurosurgeon

Article information

rID: 2296
Section: Syndromes
Tag: cases, cases
Synonyms or Alternate Spellings:
  • Bonnet-Dechaume-Blanc syndrome
  • Wyburn Mason syndrome

ADVERTISEMENT: Supporters see fewer/no ads

Cases and figures

  • Case 1
    Drag here to reorder.
  • Updating… Please wait.

     Unable to process the form. Check for errors and try again.

     Thank you for updating your details.