Yin-yang sign (solitary fibrous tumor)

The yin-yang sign is a radiologic appearance described in solitary fibrous tumor of the dura on MR.

On T2-weighted images, these tumors have two separate solid components, one that is hyperintense and one that is iso- to hypointense relative to brain parenchyma. Histologically, the former represents more hypercellular areas, while the latter represents more conspicuous collagenous stroma. The sign has also been described as a "patchy" or "black-and-white mixed" appearance. While some authors consider the appearance characteristic of solitary fibrous tumor 1-6, other authors have found it infrequently 7.

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Article information

rID: 64486
Section: Signs
Synonyms or Alternate Spellings:
  • black-and-white sign
  • yin-yang sign

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