Yolk sac tumor

Last revised by Yahya Baba on 24 Dec 2022

Yolk sac tumor (YST), also known as an endodermal sinus tumor, is a type of malignant germ cell tumor.

Epidemiology

Yolk sac tumors usually develop in infants, young children, and young women 1.

Pathology

Yolk sac tumors are non-epithelial tumors of germ-cell origin.

Location

Yolk sac tumors occur at variable sites with the ovary being the commonest.

Serological markers

Yolk sac tumors tend to secrete alpha-fetoprotein (AFP).

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