Yolk sac

Changed by Matt A. Morgan, 9 Dec 2014

Updates to Article Attributes

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The yolk sac is the first anatomical structure identified within the gestational sac. It plays a critical role in embryonal development by providing nutrients, serving as the site of initial haematopoiesis, and contributing to the development of gastrointestinalfetal gastrointestinal and reproductive systems 2

Radiographic assessmentfeatures

Ultrasound

VisualisationVisualization of a yolk sac is is useful in distinguishing an intrauterine pregnancy (IUP) from a pseudogestational sac, a decidual cast cyst or a blighted ovumanebryonic pregnancy, as it isa yolk sac is only seen in the formeran intrauterine pregnancy.

A yolk sac should always be seen when the mean sac diameter (MSD)

  • is 20 mm on trans-abdominaltransabdominal scanning and
  • and is usually seen trans-vaginallyendovaginally with an MSD of 8-10 mm.

In general if the MSD is 25 mm or greater and no fetal pole or yolk sac can be identified on trans-vaginalendovaginal scanning, then this suggests a non-viablefailed pregnancy (anembryonic pregnancy).  

In a normal early pregnancy, the diameter of the yolk sac should usually be <6 mm while its shape should be near spherical.

Visualisation of multiple yolk sacs is the earliest sign of a polyamniotic pregnancy, e.g twins.

Natural course

As the pregnancy advances, the yolk sac disappears and is often sonographically not detectable after 14-20 weeks.

See also

  • -<p>The <strong>yolk sac</strong> is first anatomical structure identified within the <a href="/articles/gestational-sac">gestational sac</a>. It plays a critical role in embryonal development by providing nutrients, serving as the site of initial haematopoiesis and contributing to the development of gastrointestinal and reproductive systems <sup>2</sup>. </p><h4>Radiographic assessment</h4><h5>Ultrasound</h5><p>Visualisation of a yolk sac is useful in distinguishing an intrauterine pregnancy (IUP) from a <a href="/articles/pseudo-gestational-sac">pseudogestational sac</a>, a <a href="/articles/decidual-cast">decidual cast cyst</a> or a <a href="/articles/anembryonic-pregnancy">blighted ovum</a>, as it is only seen in the former.</p><p>A yolk sac should always be seen when the <a href="/articles/mean-sac-diameter">mean sac diameter (MSD)</a> is 20 mm on trans-abdominal scanning and usually seen trans-vaginally with an MSD of 8-10 mm.</p><p>In general if the MSD is 25 mm or greater and no fetal pole or yolk sac can be identified on trans-vaginal scanning then this suggests a <a href="/articles/non-viable-pregnancy">non-viable pregnancy</a> (<a href="/articles/anembryonic-pregnancy">anembryonic pregnancy</a>).  </p><p>In a normal early pregnancy, the diameter of the yolk sac should usually be &lt;<strong>6</strong> mm while its shape should be near spherical.</p><p>Visualisation of multiple yolk sacs is the earliest sign of a polyamniotic pregnancy, e.g twins.</p><h5>Natural course</h5><p>As the pregnancy advances, the yolk sac disappears and is often sonographically not detectable after 14 weeks.</p><h4>See also</h4><ul><li><a href="/articles/irregular-yolk-sac">irregular yolk sac</a></li></ul>
  • +<p>The <strong>yolk sac</strong> is the first anatomical structure identified within the <a href="/articles/gestational-sac">gestational sac</a>. It plays a critical role in embryonal development by providing nutrients, serving as the site of initial haematopoiesis, and contributing to the development of fetal gastrointestinal and reproductive systems <sup>2</sup>. </p><h4>Radiographic features</h4><h5>Ultrasound</h5><p>Visualization of a yolk sac is useful in distinguishing an intrauterine pregnancy (IUP) from a <a href="/articles/pseudogestational-sac-1">pseudogestational sac</a>, a <a href="/articles/decidual-cast">decidual cast cyst</a> or a <a href="/articles/anembryonic-pregnancy">anebryonic pregnancy</a>, as a yolk sac is only seen in an intrauterine pregnancy.</p><p>A yolk sac should be seen when the <a href="/articles/mean-sac-diameter">mean sac diameter (MSD)</a></p><ul>
  • +<li>is 20 mm on transabdominal scanning</li>
  • +<li>and is usually seen endovaginally with an MSD of 8-10 mm</li>
  • +</ul><p>In general if the MSD is 25 mm or greater and no fetal pole or yolk sac can be identified on endovaginal scanning, then this suggests a <a href="/articles/non-viable-pregnancy">failed pregnancy</a> (<a href="/articles/anembryonic-pregnancy">anembryonic pregnancy</a>).  </p><p>In a normal early pregnancy, the diameter of the yolk sac should usually be &lt;<strong>6</strong> mm while its shape should be near spherical.</p><p>Visualisation of multiple yolk sacs is the earliest sign of a polyamniotic pregnancy, e.g twins.</p><h5>Natural course</h5><p>As the pregnancy advances, the yolk sac disappears and is often sonographically not detectable after 14-20 weeks.</p><h4>See also</h4><ul>
  • +<li><a href="/articles/irregular-yolk-sac">irregular yolk sac</a></li>
  • +<li><a href="/articles/calcified-yolk-sac">calcified yolk sac</a></li>
  • +</ul>

References changed:

  • 1. N Gupta and TL Angtuaco "Embryosonology in the First Trimester of Pregnancy" Ultrasound Clinics 2 (2007) 175-185. http://dx.doi.org/10.1016/j.cult.2007.07.006
  • 1. N Gupta and TL Angtuaco "Embryosonology in the First Trimester of Pregnancy" Ultrasound Clinics 2 (2007) 175-185

Tags changed:

  • first trimester
  • abr certifying ultrasound

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