Young syndrome

Young syndrome shares similar clinical and radiological findings to primary ciliary dyskinesia and cystic fibrosis, however the underlying pathogenesis yet to be fully elucidated. Obstructive azoopsermia at the level of the epididymis is thought to be the cause of infertility. The commonly referenced clinical triad are1:

  • obstructive azoospermia
  • bronchiectasis (predominantly lower lobe)
  • sinusitis (Although a well known, the actual diagnosis of sinusitis in Young's syndrome is based on case report/case series and has not been well documented in research)2.


It is named after Donald Young, an urologist who first reported a series of patients with obstructive azoospermia associate with respiratory pathology. 

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Article information

rID: 9088
Section: Syndromes
Synonyms or Alternate Spellings:
  • Young's syndrome

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