Zinc toxicity (also rarely known as zincalism) is rare as the body is remarkably efficient at excreting excess zinc. Typically oral zinc poisoning manifests primarily as:
- acute GI symptoms: vomiting, diarrhea, abdominal pain
- secondary copper deficiency
- zinc competes with copper for absorption in the small bowel
- most serious manifestation is neurotoxicity with a presentation indistinguishable from subacute combined degeneration of the cord
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