A few months ago an update has been published to the WHO classification of CNS tumors (which supersedes the 4th edition of the blue book, 2007 - although officially this version is not considered a 5th edition), which includes a substantial shift in approach, one which will have great implications in years to come.
For the first time molecular characteristics of tumors are included and in many case are more important than the histological features of various tumors.
This naturally has resulted in a flurry of activity, getting up to speed with some of the new nomenclature and updating relevant parts of the site as well as writing some missing articles. Although no doubt there are many other subtle changes in the classification which have not been captured (this would require reading the whole book, and updating every single tumor article) I hope this has captured the most notable changes.
- epithelioid glioblastoma
- diffuse leptomeningeal glioneuronal tumor
- diffuse midline glioma, H3-K27M-mutant
- ependymoma RELA fusion positive
- WHO classification of CNS tumors
- diffuse brainstem glioma
- embryonal tumor with abundant neuropil and true rosettes
- fibrillary astrocytoma
- primitive neuroectodermal tumors of the CNS
- protoplasmic astrocytoma