Thymoma

Discussion:

This young woman clinically demonstrated features of myasthenia gravis was shown to have an anterior mediastinal mass, presumably a thymoma. It was surgically excised and confirmed to be a thymoma, type B2 (cortical).

Five thymoma subtypes can be associated with myasthenia gravis: 

  1. type A (medullary)
  2. type AB (mixed)
  3. type B1 (organoid)
  4. type B2 (cortical)
  5. type B3 (well-differentiated thymic carcinoma)

Types AB, B2, and B3 thymomas are by far the most frequent subtypes and the most frequently associated with myasthenia gravis 1.  

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