Leptomeningeal enhancement - meningitis

Case contributed by Emmanouil Kalioras , 15 Jul 2022
Diagnosis almost certain
Changed by Emmanouil Kalioras, 18 Jul 2022

Updates to Case Attributes

Body was changed:

After CSF analysis, clinicians favoured the diagnosis of viral meningitis and the patient received empirical antiviral therapy. 2Two weeks followup was negative for leptomeningeal enhancement.

The sensitivity of contrast enhanced FLAIR sequences is remarkably higher in comparison to contrast enhanced T1-weighted sequences for the imaging diagnosis of meningitis. The main reason is the better distinction between enhancing meninges and enhancing cortical veins. The signal of contrast enhanced cortical veins is attenuated only on FLAIR images.1

  • -<p>After CSF analysis, clinicians favoured the diagnosis of <a title="viral meningitis" href="/articles/viral-meningitis">viral meningitis</a> and patient received antiviral therapy. 2 weeks followup was negative for <a title="leptomeningeal enhancement" href="/articles/leptomeningeal-enhancement">leptomeningeal enhancement</a>.</p><p>The sensitivity of contrast enhanced FLAIR sequences is remarkably higher in comparison to contrast enhanced T1-weighted sequences for the imaging diagnosis of meningitis. The main reason is the better distinction between enhancing meninges and enhancing cortical veins. The signal of contrast enhanced cortical veins is attenuated only on FLAIR images.</p><p> </p><p> </p><p> </p>
  • +<p>After CSF analysis, clinicians favoured the diagnosis of <a href="/articles/viral-meningitis">viral meningitis</a> and the patient received empirical antiviral therapy. Two weeks followup was negative for <a href="/articles/leptomeningeal-enhancement">leptomeningeal enhancement</a>.</p><p>The sensitivity of contrast enhanced FLAIR sequences is remarkably higher in comparison to contrast enhanced T1-weighted sequences for the imaging diagnosis of meningitis. The main reason is the better distinction between enhancing meninges and enhancing cortical veins. The signal of contrast enhanced cortical veins is attenuated only on FLAIR images. <sup>1</sup></p><p> </p><p> </p><p> </p>

References changed:

  • 1 Vaswani, A. K., Nizamani, W. M., Ali, M., Aneel, G., Shahani, B. K., & Hussain, S. (2014). Diagnostic Accuracy of Contrast-Enhanced FLAIR Magnetic Resonance Imaging in Diagnosis of Meningitis Correlated with CSF Analysis. ISRN radiology, 2014, 578986. https://doi.org/10.1155/2014/578986
  • Vaswani, A. K., Nizamani, W. M., Ali, M., Aneel, G., Shahani, B. K., &amp; Hussain, S. (2014, March 20). Diagnostic accuracy of contrast-enhanced Flair magnetic resonance imaging in diagnosis of meningitis correlated with CSF analysis. ISRN radiology. Retrieved July 18, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062848/#!po=76.5625

How to use cases

You can use Radiopaedia cases in a variety of ways to help you learn and teach.

Creating your own cases is easy.