Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS)

Discussion:

Widespread areas of apparent ischemia of varying ages in non-vascular territories, some with reduced ADC and some without - there is an ongoing debate about whether the stroke-like incidents in MELAS are ischemic or metabolic or both.          

This patient has a family history of mitochondrial disease.        

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