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What is the differential diagnosis?
1. Benign expansion of subarachnoid spaces: no parenchymal abnormalities are seen in this condition. 2. Other causes of bilateral basal ganglia high T2 intensity: amino acidopathies, mitochondrial diseases, Wilson's disease, Zellweger syndrome.
Younger brother scanned at 8 mth of age
The findings are similar to his older brother, but note that there is less volume loss of the putamina and globus pallidi. Also, no tegmental abnormality is seen at this stage.
Wide CSF spaces anterior to the temporal poles and in the Sylvian fissures are again seen, but in this case, the prominence of extra-axial CSF spaces over the convexity is better appreciated.